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Affiliation |
Faculty of Engineering, Division of Materials Science and Chemical Engineering |
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Job Title |
Assistant Professor |
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Research Fields, Keywords |
DNA, NMR, isotope labeling, organic chemistry, RNA |
SAKURABAYASHI Shuhei
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The Best Research Achievement in Research Career 【 display / non-display 】
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【Published Thesis】 NMR-Based Rational Drug Design of G:G Mismatch DNA Binding Ligand Trapping Transient Complex via Disruption of a Key Allosteric Interaction 2025.04
【Published Thesis】 The heterodimer of 2-amino-1,8-naphthyridine and 3-aminoisoquinoline binds to the CTG/CTG triad via hydrogen bonding(Bioorganic & Medicinal Chemistry Letters) 2024.10
【Published Thesis】 NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA(NUCLEIC ACIDS RESEARCH) 2022.09
The Best Research Achievement in the last 5 years 【 display / non-display 】
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【Published Thesis】 NMR-Based Rational Drug Design of G:G Mismatch DNA Binding Ligand Trapping Transient Complex via Disruption of a Key Allosteric Interaction 2025.04
【Published Thesis】 The heterodimer of 2-amino-1,8-naphthyridine and 3-aminoisoquinoline binds to the CTG/CTG triad via hydrogen bonding(Bioorganic & Medicinal Chemistry Letters) 2024.10
【Published Thesis】 NMR analysis of #U15#URN-labeled naphthyridine carbamate dimer (NCD) to contiguous CGG/CGG units in DNA 2024.02
【Published Thesis】 Robust Enzymatic Production of DNA G-Quadruplex, Aptamer, DNAzyme, and Other Oligonucleotides: Applications for NMR( J. Am. Chem. Soc.) 2024.01
【Published Thesis】 NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA(NUCLEIC ACIDS RESEARCH) 2022.09
Education 【 display / non-display 】
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2021.4-2024.3
Osaka University Doctor Course Completed
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2019.4-2021.3
Osaka University Master Course Completed
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2015.4-2019.3
Osaka University Graduated
Campus Career 【 display / non-display 】
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2024.4
Duty Yokohama National UniversityFaculty of Engineering Division of Materials Science and Chemical Engineering Assistant Professor
Research Areas 【 display / non-display 】
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Natural Science / Biophysics, chemical physics and soft matter physics
Papers 【 display / non-display 】
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NMR-Based Rational Drug Design of G:G Mismatch DNA Binding Ligand Trapping Transient Complex via Disruption of a Key Allosteric Interaction
Shuhei Sakurabayashi, Kyoko Furuita, Takeshi Yamada, Noriaki Sugiura, Makoto Nomura, Takanori Nakan … Show more authors
Shuhei Sakurabayashi, Kyoko Furuita, Takeshi Yamada, Noriaki Sugiura, Makoto Nomura, Takanori Nakane, Akihiro Kawamoto, Genji Kurisu, Yohei Miyanoiri, Toshimichi Fujiwara, Kazuhiko Nakatani, and Chojiro Kojima Hide authors
2025.4
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Single Work
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The heterodimer of 2-amino-1,8-naphthyridine and 3-aminoisoquinoline binds to the CTG/CTG triad via hydrogen bonding
Shuhei Sakurabayashi, Takeshi Yamada, Kazuhiko Nakatani
Bioorganic & Medicinal Chemistry Letters 114 2024.10 [Reviewed]
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Joint Work
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Yamada, T; Furuita, K; Sakurabayashi, S; Nomura, M; Kojima, C; Nakatani, K
NUCLEIC ACIDS RESEARCH 50 ( 17 ) 9621 - 9631 2022.9
Language：Japanese Publishing type：Research paper (scientific journal) Joint Work
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NMR analysis of 15N-labeled naphthyridine carbamate dimer (NCD) to contiguous CGG/CGG units in DNA
Takeshi Yamada, Shuhei Sakurabayashi, Noriaki Sugiura, Hitoshi Haneok and Kazuhiko Nakatani
60 ( 27 ) 3645 - 3648 2024.2
Language：English Publishing type：Research paper (scientific journal) Single Work
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Robust Enzymatic Production of DNA G-Quadruplex, Aptamer, DNAzyme, and Other Oligonucleotides: Applications for NMR
Xi Wang, Binhan Yu, Shuhei Sakurabayashi, Jonathan M. Paz-Villatoro, Junji Iwahara
J. Am. Chem. Soc. 146 ( 3 ) 1748 - 1752 2024.1 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Single Work