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Affiliation |
Faculty of Engineering, Division of Materials Science and Chemical Engineering |
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Job Title |
Assistant Professor |
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Related SDGs |
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Seo Jieun
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Education 【 display / non-display 】
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2015.3-2021.8
Seoul National University Department of Biomedical Sciences Doctor Course Completed
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2011.4-2015.3
Yokohama National University Department of Chemistry, Chemical Engineering and Life Science Graduated
Degree 【 display / non-display 】
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Doctor of Philosophy in Medical Science - Seoul National University(Korea)
Campus Career 【 display / non-display 】
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2022.4
Duty Yokohama National UniversityFaculty of Engineering Division of Materials Science and Chemical Engineering Assistant Professor
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2023.4
Concurrently Yokohama National UniversityInstitute of Advanced Sciences Assistant Professor
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2022.4
Concurrently Yokohama National UniversityCollege of Engineering Science Department of Chemistry, Chemical Engineering and Life Science Assistant Professor
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2022.4
Concurrently Yokohama National UniversityGraduate school of Engineering Science Department of Chemistry, Chemical Engineering and Life Science Assistant Professor
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2022.2-2022.3
Concurrently Yokohama National UniversityFaculty of Engineering Division of Materials Science and Chemical Engineering Assistant Professor
External Career 【 display / non-display 】
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2022.4
Kanagawa Institute of Industrial Science and Technology Researcher
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2022.1-2022.3
Kanagawa Institute of Industrial Science and Technology Researcher
Academic Society Affiliations 【 display / non-display 】
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2024
The Japanese Society for Alternatives to Animal Experiments
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2024
Society for Chemistry and Micro-Nano Systems
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2023
The Molecular Biology Society of Japan
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2023
The Society for Hair Science Research
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2022
The Japanese Society for Regenerative Medicine
Research Areas 【 display / non-display 】
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Life Science / Biomedical engineering
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Life Science / Physiology
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Life Science / Molecular biology
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Life Science / Tumor biology
Papers 【 display / non-display 】
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Effects of oxytocin receptor agonists on hair growth promotion
Kageyama, T; Seo, J; Yan, L; Fukuda, J
SCIENTIFIC REPORTS 14 ( 1 ) 2024.10
Language：English Publishing type：Research paper (scientific journal) Joint Work
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Kageyama, T; Seo, J; Yan, L; Fukuda, J
SCIENTIFIC REPORTS 14 ( 1 ) 2024.2 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
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Kageyama Tatsuto, Seo Jieun, Yan Lei, Fukuda Junji
Scientific Reports 14 ( 1 ) 2024.2
Language：English Publishing type：Research paper (scientific journal) Publisher：Nature Portfolio Joint Work
Considerable global demand exists for the development of novel drugs for the treatment of alopecia. A recent report demonstrated that oxytocin promotes hair growth activity in human dermal papilla (DP) cells; however, its application in drugs or cosmetic products is challenging because rapid degradation and relatively large molecular weight prevent long-term topical administration on the scalp. Here, we examined cinnamic acid, a small molecule activator for oxytocin receptor (OXTR) expression. Treatment with cinnamic acid led to upregulation of OXTR and trichogenic gene expression in human DP cells. Furthermore, inhibition of OXTR with an antagonist, L-371,257, suppressed hair growth-related gene expression in DP cells. These findings suggest that cinnamic acid enhances the hair growth ability of DP cells via oxytocin signaling. Additionally, we tested the hair growth-promoting effects of cinnamic acid using hair follicle organoids in vitro and observed that cinnamic acid significantly promoted the growth of hair peg-like sprouting. These promising results may be useful for developing hair growth-promoting products targeting oxytocin.
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Effects of the PI3K/Akt signaling pathway on the hair inductivity of human dermal papilla cells in hair beads
Seibutsu-kogaku Kaishi 102 ( 2 ) 65 - 65 2024.2
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Society for Biotechnology, Japan Joint Work
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Exosomes for hair growth and regeneration
Zhou, YH; Seo, J; Tu, S; Nanmo, A; Kageyama, T; Fukuda, J
JOURNAL OF BIOSCIENCE AND BIOENGINEERING 137 ( 1 ) 1 - 8 2024.1 [Reviewed]
Language：The in addition, foreign language Publishing type：Research paper (scientific journal) Joint Work
Awards 【 display / non-display 】
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第23回日本再生医療学会総会優秀演題賞
2024.3 日本再生医療学会 毛髪再生機能向上のためのHypoxia-inducible factor-1aメカニズムの応用
Individual or group name of awards：SEO JIEUN
Grant-in-Aid for Scientific Research 【 display / non-display 】
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ヒト毛乳頭細胞の発毛活性に対するHIF-1シグナルの毛髪再生への応用
2023 - 2025
Grant-in-Aid for Early-Career Scientists
Other external funds procured 【 display / non-display 】
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毛髪再生医療のためのヒト毛包オルガノイドの開発
2023.7 - 2026.3
Japan Agency for Medical Research and Development
Authorship：Coinvestigator(s)
Charge of on-campus class subject 【 display / non-display 】
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2024 Basic Laboratory for Chemistry, Chemical Engineering and Life Science 2
College of Engineering Science Department of Chemistry, Chemical Engineering and Life Science
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2024 Chemistry Laboratory and Exercise
College of Engineering Science Department of Chemistry, Chemical Engineering and Life Science
Academic Activities 【 display / non-display 】
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日本動物実験代替法学会広報委員会
Role(s)： Other
2024
Type：Academic society, research group, etc.