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Affiliation |
Faculty of Engineering, Division of Intelligent Systems Engineering |
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Job Title |
Assistant Professor |
Yan Lei
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Degree 【 display / non-display 】
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Doctor of Engineering - Yokohama National University
Campus Career 【 display / non-display 】
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2022.4
Duty Yokohama National UniversityFaculty of Engineering Division of Materials Science and Chemical Engineering Assistant Professor
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2023.4
Concurrently Yokohama National UniversityInstitute of Advanced Sciences Assistant Professor
Papers 【 display / non-display 】
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Regenerative potential of CD200<SUP>-</SUP> subpopulations of hair follicle bulge
Sun, T; Hamano, S; Chen, J; Ling, LC; Lin, JR; Yan, L; Kageyama, T; Wu, FY; Tan, ZL; Wu, WY; Fukuda … Show more authors
Sun, T; Hamano, S; Chen, J; Ling, LC; Lin, JR; Yan, L; Kageyama, T; Wu, FY; Tan, ZL; Wu, WY; Fukuda, J Hide authors
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 14 2026.4
Language:English Publishing type:Research paper (scientific journal) Joint Work
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Kageyama, T; Anakama, R; Hamano, S; Tu, S; Migita, Y; Asaba, T; Nanmo, A; Ishikawa, K; Yan, L; Seo, … Show more authors
Kageyama, T; Anakama, R; Hamano, S; Tu, S; Migita, Y; Asaba, T; Nanmo, A; Ishikawa, K; Yan, L; Seo, J; Fukuda, J Hide authors
ACS BIOMATERIALS SCIENCE & ENGINEERING 12 ( 3 ) 1704 - 1714 2026.3
Language:English Publishing type:Research paper (scientific journal) Joint Work
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He, YX; Cheng, L; Shen, HX; Wei, CN; Yan, LS; Zou, XH
IEEE MICROWAVE AND WIRELESS TECHNOLOGY LETTERS 35 ( 12 ) 1897 - 1900 2025.12
Language:English Publishing type:Research paper (scientific journal) Joint Work
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Serotonin activates dermal papilla cells and promotes hair growth
Seo Jieun, Kageyama Tatsuto, Yan Lei, Hamano Sayuri, Fukuda Junji
Scientific Reports 15 ( 1 ) 24525 2025.7
Language:English Publishing type:Research paper (scientific journal) Publisher:Springer Nature Joint Work
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that plays a vital role in regulating behavior, mood, memory, and gastrointestinal homeostasis. Although recent studies have identified an intestine-hair follicle link, potentially implicating 5-HT, its exact relationship with hair growth remains unclear. Here we investigated the effects of serotonin signaling on hair follicle homeostasis. Gene expression analysis showed significant upregulation of hair growth-related genes in dermal papilla cells treated with 5-HT. The hair growth-promoting effects of 5-HT were examined using hair follicle organoids and hair follicle organ cultures. The addition of 5-HT to hair follicle organoids and hair follicles promoted hair shaft elongation. Similar effects were observed with sumatriptan succinate, a 5-HT receptor agonist. These results suggest that targeting serotonin signaling can advance alopecia therapy.
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Serotonin activates dermal papilla cells and promotes hair growth
Kageyama, T; Seo, J; Yan, L; Hamano, S; Fukuda, J
SCIENTIFIC REPORTS 15 ( 1 ) 24525 2025.7
DOI Web of Science PubMed Repository
Language:English Publishing type:Research paper (scientific journal) Publisher:Springer Nature Joint Work