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Affiliation |
Faculty of Engineering, Division of Intelligent Systems Engineering |
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Job Title |
Professor |
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Research Fields, Keywords |
transition metal oxide, nanoparticles, Drug Delivery System, magnetization measurement, nanotechnology, nanomedicine, multiferroic |
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Mail Address |
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YNU Research Center |
Research Center for Nanoscopic Physics and Nanomedicine |
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Related SDGs |
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ICHIYANAGI Yuko
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ORCID
The Best Research Achievement in the last 5 years 【 display / non-display 】
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【Book】 Extracellular Fine Particles Chapter 13 “Magnetic nanoparticles for diagnostics and therapy”(Springer) 2024.02
【Published Thesis】 Magnetically Induced Brownian Motion of Iron Oxide Nanocages in Alternating Magnetic Fields and Their Application for Efficient siRNA Delivery(NANO LETTERS) 2022.11
【Awards】 The Japan Society of Calorimetry and Thermal Analysis [Society Award] 2024.09
【Presentation(International conference)】 Heat Dissipation Properties and MR Effect on Magnetic Nanoparticles(5th International Conference on Emerging Advanced Nanomaterials (ICEAN-2024)) 2024.11
【Presentation(International conference)】 Magnetic Relaxation Characteristic and Cancer Cell Suppression Effect of Magnetic Nanoparticles(IEEE Nanomaterials Applications & Properties NAP-2024 ) 2024.09
YNU Research Center 【 display / non-display 】
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Research Center for Nanoscopic Physics and Nanomedicine
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Research Center for Advanced manufacturing technologies and life innovation
Education 【 display / non-display 】
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-1996
Yokohama National University Completed
Degree 【 display / non-display 】
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Master of Education - Yokohama National University
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Doctor of Engineering - Yokohama National University
Campus Career 【 display / non-display 】
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2019.10
Duty Yokohama National UniversityFaculty of Engineering Division of Intelligent Systems Engineering Professor
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2009.1-2019.9
Duty Yokohama National UniversityFaculty of Engineering Division of Intelligent Systems Engineering Associate Professor
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2007.4-2008.12
Duty Yokohama National UniversityFaculty of Engineering Division of Intelligent Systems Engineering Lecturer
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2001.4-2007.3
Duty Yokohama National UniversityFaculty of Engineering Division of Intelligent Systems Engineering Research Assistant
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1997.4-2001.3
Duty Yokohama National UniversitySchool of Engineering Research Assistant
Academic Society Affiliations 【 display / non-display 】
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2018.12
IEEE Magnetics Society
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2014.9
日本応用物理学会
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2002.6
ナノ学会
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Surface Science Society of Japan
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America-Japan Nanomedicine Society
Research Areas 【 display / non-display 】
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Nanotechnology/Materials / Nano/micro-systems
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Natural Science / Magnetism, superconductivity and strongly correlated systems / Low Temperature Magnetism
Research Career 【 display / non-display 】
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Nanomedicine
Project Year：
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Magnetism on nanoscopic system
Project Year：
Books 【 display / non-display 】
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Extracellular Fine Particles Chapter 13 “Magnetic nanoparticles for diagnostics and therapy”
Yuko Ichiyanagi（ Role： Sole author）
Springer [Reviewed]
Language：English Book type：Scholarly book
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Cell-inspired materials and engineering, "Magnetic nanoparticles and alternating magnetic field for cancer therapy"
Harutaka Mekaru, Yuko Ichiyanagi, Fuyuhiko Tamanoi（ Role： Joint author）
Springer （ ISBN: 978-3030559236 ）
Total pages：284 Language：English Book type：Scholarly book
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Nanomaterials for Biomedical Applications: Synthesis, Characterization, and Applications
M. Bououdina, S. Rashdan, J. L. Bobet and Y. Ichiyanagi（ Role： Joint author）
Journal of Nanomaterials
Language：English Book type：Scholarly book
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Analysis of Complex Materials using Functionalized Magnetic Nanoparticles,Magnetic Nanoparticles: Properties, Synthesis and Applications
Shu Taira, Yuko Ichiyanagi（ Role： Joint author）
Nova Publishers
Language：English Book type：Scholarly book
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"Preparation of Magnetic Nanoparticles Using Chemical Route and Functionalization for Medical Applications", "NANOMAGNETISM AND SPINTRONICS"
Yuko Ichiyanagi（ Role： Sole author）
World Scientific
Language：English Book type：Scholarly book
Thesis for a degree 【 display / non-display 】
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Ni(CH)2単層ナノクラスターの磁気相転移
一柳 優子
1996.3
Doctoral Thesis Single Work
横浜国立大学 工学研究科
ニッケル塩化物水溶液とメタ珪酸ナトリウム水溶液との混合により生じた沈殿物に，直径が約2.5 nmの水酸化ニッケルの単層クラスターが存在することを明らかにした。バルクの水酸化ニッケルは反強磁性であるにも関わらず，このクラスターは10 Kの低温で強磁性転移を起こすことを見出し，世界で始めて単層の強磁性を実現した。直流および交流磁化率の測定を中心に，ナノサイズに特徴的な磁気特性について記述した。
Papers 【 display / non-display 】
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Magnetic relaxation of Gd doped MnFe2O4 nanoparticles for MR effect and heat dissipation
Noboru Kataoka, Akihito Usui, Yuu Kususmoto, Hiroki Amano, and Yuko Ichiyanagi
IEEE Trans. Magn. 2025.4
Authorship：Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Single Work
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Improvement of Water Dispersion of Magnetic Nanoparticles and Their Effect on Magnetic Relaxation
Watanabe, S; Yano, R; Amano, H; Abe, R; Kusumoto, Y; Hasegawa, M; Ichiyanagi, Y
E-JOURNAL OF SURFACE SCIENCE AND NANOTECHNOLOGY advpub ( 0 ) 2025.4 [Reviewed]
DOI Web of Science CiNii Research
Language：English Publishing type：Research paper (scientific journal) Publisher：公益社団法人 日本表面真空学会 Joint Work
<p>Magnetic relaxation is a critical phenomenon in the application of magnetic nanoparticles (MNPs) in magnetic hyperthermia therapy and imaging. Effective magnetic relaxation time is an essential factor for understanding the relaxation process. Because the hydrodynamic volume is proportional to the Brownian relaxation time, it represents a significant parameter in this context. Because MNPs tend to aggregate, aggregates must be considered when determining hydrodynamic volumes, and several studies have adopted single-core models. However, in this study, we distinguished between the primary particle size (PPS), which refers to the diameter of individual MNPs, and secondary particle size (SPS), which represents the diameter of aggregates. We investigated whether conventional magnetic relaxation models could be applied under these considerations. The magnetic susceptibility calculated from the distributions of PPS and SPS was compared with that estimated from heat generation under an alternating magnetic field, revealing the importance of SPS in the discussion of Brownian relaxation. Furthermore, we conducted experiments on silica coating and ultrasonic treatment as strategies to reduce the average and variance of the SPS of MNPs. The experiments identified the optimal conditions for the ratio of MNPs to tetraethyl orthosilicate in the silica coating and exposure time of the ultrasonic treatment. The findings of this study present effective strategies for designing SPS of MNPs and provide evidence that aggregates are essential for understanding the magnetic properties of MNPs.</p>
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Amano, H; Abe, R; Watanabe, S; Kusumoto, Y; Ichiyanagi, Y
PHYSICAL CHEMISTRY CHEMICAL PHYSICS 2025.3 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
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T. Sakamoto, K. Nii, Y. Fujita, T. Moriwaki, H. Amano, R. Abe, Y. Ichiyanagi
AIP Advances 14 ( 1 ) 2024.1 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Single Work
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Magnetic properties and XAFS analysis of PEG-coated Gd-doped ZnO nanoparticles
Kazune Nii; Hiroki Amano; Kentaro Ohara; Kenta Nakazawa; Takeshi Sakamoto; Tomomasa Moriwaki; Yohei … Show more authors
Kazune Nii; Hiroki Amano; Kentaro Ohara; Kenta Nakazawa; Takeshi Sakamoto; Tomomasa Moriwaki; Yohei Fujita; Yuko Ichiyanagi Hide authors
IEEE Transactions on Magnetics 59 ( 11 ) 1 - 5 2023.6 [Reviewed]
DOI Web of Science CiNii Research
Authorship：Last author Language：English Publishing type：Research paper (scientific journal) Publisher：Institute of Electrical and Electronics Engineers (IEEE) Joint Work
In this study, polyethylene glycol (PEG)-coated Gd-doped zinc oxide (ZnO) nanoparticles were prepared by the one-pot solvothermal method. X-ray diffraction (XRD) measurements indicated that all the prepared samples had a wurtzite structure. The size of the nanoparticles could be controlled to be approximately 15 nm. Magnetization measurements using a superconducting quantum interference device (SQUID) magnetometer indicated that the saturation magnetization was enhanced by Gd doping. Local structure analysis by X-ray absorption fine structure (XAFS) measurements revealed the presence of oxygen vacancies, suggesting that this is related to the increased magnetization of the prepared samples.
Review Papers 【 display / non-display 】
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Hyperthermia Effect by AC Magnetic Susceptibility and Heat Dissipation of Magnetic Nanoparticles
Netsu Sokutei 42 ( 4 ) 148 - 152 2015.10 [Reviewed] [Invited]
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Publisher：Japan Society of Calorimetry and Thermal Analysis Single Work
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普通に生きることの難しさ、その大切さ
一柳優子
日本磁気学会誌 まぐね 19 ( １ ) 2024.2 [Reviewed] [Invited]
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Single Work
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「俯瞰区分と研究開発領域」ナノDDS・セラノスティクス
一柳優子
CRDS「研究開発の俯瞰報告書 ナノテクノロジー・材料分野（2019年）」 2020
Language：Japanese Publishing type：Other Single Work
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Cu-Znフェライトナノ微粒子の磁気特性と医療応用
藤原康暉、木村慎司、宮野俊太、井手太星、臼井章仁、斉藤春夫、細貝良行、一柳優子
ナノ学会会報 17 ( 2 ) 61 - 67 2019.3
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Joint Work
藤原康暉、木村慎司、宮野俊太、井手太星、臼井章仁、斉藤春夫、細貝良行、一柳優子、“Cu-Znフェライトナノ微粒子の磁気特性と医療応用”、ナノ学会会報 第１７巻 第2号、pp.61-67、２０１９年３月
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ナノテクノロジー・材料分野
一柳優子 外
ＪＳＴ研究開発の俯瞰報告書 2019
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Joint Work
ＪＳＴ研究開発の俯瞰報告書 ナノテクノロジー・材料分野2019
Industrial Property Rights 【 display / non-display 】
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ナノ微粒子、及びナノ微粒子の製造方法、並びに抗腫瘍剤（日本）
一柳優子
Application no：PCT/JP2019/008494 Date applied：2019.3.5
Country of applicant：Domestic
ＰＣＴ特許出願： 「ナノ微粒子、及びナノ微粒子の製造方法、並びに抗腫瘍剤」
国際出願番号：PCT/JP2019/008494
出願日：平成３１年３月５日 -
ナノ微粒子、及びナノ微粒子の製造方法
一柳 優子, 橋本 達哉, 千本松 孝明, 阿部 真之, 田中 秀吉
Application no：2018-038989 Date applied：2018.3.5
Country of applicant：Domestic
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質量分析用マトリクス剤、質量分析方法、及び質量分析イメージング方法
一柳優子、森本翔大
Applicant：横浜国立大学
Application no：特願2016-037758 Date applied：2016.2.29
Country of applicant：Domestic
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温熱療法用Ni-Zn系フェライト磁気ナノ微粒子、及びそれを用いた温熱療法用薬物結合複合体
一柳優子、竹内宏賢、大類翔太
Applicant：横浜国立大学
Application no：特願2012-133436 Date applied：2012.6.13
Country of applicant：Domestic
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マグネタイトナノ微粒子の製造方法
一柳 優子
Application no：2010-109165 Date applied：2010.5.11
Announcement no：2011-236086 Date announced：2011
Patent/Registration no：特許第5670094号 Date issued：2014.12.26
Country of applicant：Domestic
Awards 【 display / non-display 】
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The Japan Society of Calorimetry and Thermal Analysis [Society Award]
2024.9 The Japan Society of Calorimetry and Thermal Analysis Study of heat dissipation properties of magnetic nanoparticles and their biomedical application
Individual or group name of awards：Yuko Ichiyanagi
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Best Poster Award
2024.9 IEEE NAP2024 Exploring the Optical and Magnetic Properties of Molecular Beam Epitaxy-Grown Diluted Multicomponent III-V Semiconductor Nanofilms
Individual or group name of awards：Nataliia Tataryn et al.
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2023.9 日本磁気学会 INTERMAG2023 の仙台開催を通した磁気工学並びに関連分野への貢献
Individual or group name of awards：一柳優子、他（INTERMAG2023 組織委員会）
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2020.11 Christopher Marrows, (General Chair, MMM2020 Virtual Conference) Modification of thiol groups on magnetic nanoparticles for theranostics
Individual or group name of awards：Yuko Ichiyanagi
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The 64th JSAP Spring Meeting, 2017
2017.4 Thw Japan Society of Applied Physics Magnetic Hyperthermia and MR effect and mangetic properties of Mn0.8-xCoxZn0.2Fe2O4
Individual or group name of awards：Tomoya Ishikawa, Yuko Ichiyanagi, et al.
Grant-in-Aid for Scientific Research 【 display / non-display 】
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スーパースピングラス磁気ナノ微粒子の創製とナノ・セラノスティクスの実現
2020.4 - 2024.3
科学研究費補助金 Grant-in-Aid for Scientific Research(A)
Grant type：Competitive
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温熱療法を目指したスーパースピングラス磁気ナノ微粒子の創製と医療への応用
2017.4 - 2021.3
科学研究費補助金 Grant-in-Aid for Scientific Research(B)
Investigator(s)：一柳優子
Grant type：Competitive
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磁気ナノ微粒子の優れたイオン化支援機能の探求と質量分析イメージングへの応用
2017.4 - 2020.3
科学研究費補助金 Grant-in-Aid for Challenging Research (Exploratory)
Investigator(s)：一柳優子
Grant type：Competitive
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磁気ハイパーサーミアの実現とネール緩和に従う超常磁性ナノ微粒子の開発
2013.4 - 2017.3
科学研究費補助金 Grant-in-Aid for Scientific Research(B)
Grant type：Competitive
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がん細胞特異的磁気ナノ微粒子のハイパーサーミアへの応用
2011.4 - 2014.3
科学研究費補助金 Grant-in-Aid for Exploratory Research
Grant type：Competitive
Other external funds procured 【 display / non-display 】
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絶好調維持システムを目指した先制治療「ナノ・セラノスティクス」の実現
2017.11 - 2019.3
Japan Science and Technology Agency 未来社会創造事業
Investigator(s)：一柳優子
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鉄系酸化物磁気ナノ微粒子の形状制御と磁気及び熱力学的特 性分析
Grant number：21 2024.4 - 2025.3
東工大フロンティア 2024度共同利用研究
Investigator(s)：一柳優子
Authorship：Principal investigator
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セラノスティクス機能を持つ磁気ナノ微粒子の開発
Grant number：H-48 2023.4 - 2025.3
Japan Agency for Medical Research and Development 橋渡し研究プログラム 異分野シーズ
Investigator(s)：一柳優子
Authorship：Principal investigator
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GdをドープしたFerrite磁気ナノ微粒子の磁気特性
Grant number：13 2023.4 - 2024.3
東工大フロンティア 共同利用研究
Authorship：Principal investigator
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がん温熱療法と診断を目指した磁気ナノ微粒子の創製
Grant number：No.280118 2022.4 - 2023.3
Private Foundations 渡邉財団磁気研究助成 28回研究助成
Authorship：Principal investigator
Presentations 【 display / non-display 】
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一柳優子 [Invited]
2024年第71回応用物理学会春季学術講演会シンポジウム 2024.3 日本応用物理学会
Event date： 2024.3
Language：Japanese Presentation type：Oral presentation (invited, special)
Venue：東京都市大学 世田谷キャンパス Country：Japan
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Magnetic Nanoparticles for Theranostics
Yuko Ichiyanagi [Invited]
European Materials Research Society Spring Meeting 2023 (EMRS) 2023.6 European Materials Research Society
Event date： 2023.5 - 2023.6
Language：English Presentation type：Oral presentation (keynote)
Venue：Strasbourg Country：France
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Magnetic nanoparticles for diagnostics and therapy
Yuko Ichiyanagi [Invited]
Pacifichem 2021.12
Event date： 2021.12
Language：English Presentation type：Oral presentation (invited, special)
Venue：USA (Remote) Country：United States
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Magnetic relaxation and heat dissipation of functional magnetic nanoparticles
Yuko Ichiyanagi [Invited]
Pacifichem 2021.12
Event date： 2021.12
Language：English Presentation type：Oral presentation (invited, special)
Venue：USA (Remote) Country：United States
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ナノ・セラノスティクスを目指した磁気ナノ微粒子の創製
一柳優子 [Invited]
2025年第72回応用物理学会春季学術講演会 2025.3 日本応用物理学会
Event date： 2025.3
Language：Japanese Presentation type：Oral presentation (invited, special)
Venue：東京理科大学 野田キャンパス Country：Japan
Past of Collaboration and Commissioned Research 【 display / non-display 】
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Engineering of nanoparticles and nanostructures diluted magnetic semiconductors
Offer organization: V.E. Lashkaryov Institute of Semiconductor Physics of NAS of Ukraine, Kyiv International Cooperative Research
Project Year： 2023.11 - 2024.5
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magnetic nanoparticles for biomedical applications
Offer organization: コーネル大学 International Cooperative Research
Project Year： 2021.5 - 2025.12
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Magnetic nanoparticles for Theranostics
Offer organization: オビエド大学 International Cooperative Research
Project Year： 2020.1 - 2025.12
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機能性ナノ微粒子
Cooperative Research within Japan
Project Year： 2005.5 -
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γ-αphase coexistent Fe2O3 ferromagnetic nanoclusters for magnetic mectia
Funded Research offered by Enterprises
Project Year： 2001 - 2001
Charge of on-campus class subject 【 display / non-display 】
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2025 Advanced Magnetics
Graduate school of Engineering Science
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2025 Career-Design in Physics
Graduate school of Engineering Science
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2025 Current Topics in Modern Physics
Graduate school of Engineering Science
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2025 Nanophysics and Advanced Materials
Graduate school of Engineering Science
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2025 Experimental Practice in Physics
College of Urban Sciences
Committee Memberships 【 display / non-display 】
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CREST領域アドバイザー
2019.4 - 2021.3 領域アドバイザー
Committee type：Academic society
https://www.jst.go.jp/kisoken/crest/research_area/ongoing/bunyah29-1.html
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JST S-イノベ
2018.10 - 2019.3 中間評価委員
Committee type：Academic society
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International Conference on Fine Particle Magnetism
2016.6 Steering committee
Committee type：Academic society
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IEEE Magnetics Society Administrative Committee
2025.1 Administrative Committee
Committee type：Academic society
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IEEE Technical Committee
2025.1
Committee type：Academic society
Social Contribution(Extension lecture) 【 display / non-display 】
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2024 Women in Magnetism Leadership Workshop: Effective Communication and Conflict Resolution
Role(s)： Host, Planner, Logistic support
2024.11
Audience： Graduate students, Researchers
Type：Seminar, workshop
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Women's Workshop for Emerging Leaders in Science
Role(s)： Host, Planner, Logistic support
2023.11
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東京新聞「世界女性デー 壁のない社会に」
Role(s)： Filming support
東京新聞 2021.3
Audience： University students, Graduate students, Researchers, General public, Company, Other
Type：Newspaper, magazine
一柳優子 教授（横浜国立大学）
「コロナ禍で噴出した社会のひずみが女性たちを追い詰めている。女性の人権を考え、行動する8日の「国際女性デー」に合わせ、神奈川県内の人に聞いた。」
掲載日：2021年3月8日 -
産学連携イノベーション創出イベント「百人百様×サイエンス」
ダイバーシティ連携協議会KT 横浜 2020.3
Audience： University students, Graduate students, Researchers, General public, Scientific organization, Company, Government agency, Other
Type：Lecture
一柳優子，
「産学連携イノベーション創出イベント」マッチングに成功した事例。
2020年3月30日 -
日米ナノテク若手研究者交流シンポジウム
文科省、アメリカＮＳＦ 東京 2006.12
Media Coverage 【 display / non-display 】
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「声をつないで」旧姓使用求め象牙の塔で奮闘
毎日新聞 毎日新聞電子版 2020.3
一柳優子
2020年3月9日 https://mainichi.jp/articles/20200305/k00/00m/040/271000c