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IIJIMA Kazutoshi
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【Published Thesis】 Hydroxyapatite Particles from Simulated Body Fluids with Different pH and Their Effects on Mesenchymal Stem Cells 2021.09
【Published Thesis】 Fabrication and Characterization of Polysaccharide Composite Films from Polyion Complex Particles 2020.02
【Published Thesis】 Analysis of the formation mechanism of polyion complexes of polysaccharides by molecular dynamics simulation with oligosaccharides 2022.03
【Published Thesis】 Analysis of the formation mechanism of polyion complexes of polysaccharides by molecular dynamics simulation with oligosaccharides 2022.03
【Published Thesis】 Hydroxyapatite Particles from Simulated Body Fluids with Different pH and Their Effects on Mesenchymal Stem Cells 2021.09
【Published Thesis】 Microfabrication of Gelatin Methacrylate/Hydroxyapatite Composites by Utilizing Alternate Soaking Process(ACS BIOMATERIALS SCIENCE & ENGINEERING) 2023.11
【Published Thesis】 Specific ion effects on the aggregation of polysaccharide-based polyelectrolyte complex particles induced by monovalent ions within Hofmeister series(JOURNAL OF COLLOID AND INTERFACE SCIENCE) 2023.08
【Published Thesis】 Analysis of the aggregation mechanism of chondroitin sulfate/chitosan particles and fabrication of hydrogel cell scaffolds(INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES) 2022.06
Doctor of Engineering - Keio University
Master of Engineering - Keio University
Duty Yokohama National UniversityFaculty of Engineering Division of Materials Science and Chemical Engineering Associate Professor
Concurrently Yokohama National UniversityInstitute of Advanced Sciences Associate Professor
Concurrently Yokohama National UniversityGraduate School of Engineering Department of Materials Science and Engineering Associate Professor
Concurrently Yokohama National UniversityCollege of Engineering Science Department of Chemistry, Chemical Engineering and Life Science Associate Professor
Concurrently Yokohama National UniversityGraduate school of Engineering Science Department of Chemistry, Chemical Engineering and Life Science Associate Professor
Cell Processing Technology
Kazutoshi Iijima, Makoto Yamazaki（ Role： Sole author , Chapter 5 Polysaccharide-Based Cell Scaffolds for Cartilage Regeneration）
Springer Singapore （ ISBN:978-981-97-4255-4 ）
Responsible for pages：93-103 Language：English Book type：Scholarly book
Nanostructured Materials: Synthesis, Properties and Applications
Mineo Hashizume,Kazutoshi Iijima,Yusuke Yataka（ Role： Contributor）
NOVA science publishers （ ISBN:978-1-53615-013-1 ）
Language：English Book type：Scholarly book
ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発-
（ Role： Contributor）
シーエムシー出版 （ ISBN:9784781313337 ）
Language：Japanese Book type：Scholarly book
Advances in Chemistry Research
Shohei Ishikawa, Kazutoshi Iijima, Yuta Yahagi, Hidenori Otsuka（ Role： Joint author）
Nova Science Publishers （ ISBN:9781536138382 ）
Total pages：264 Responsible for pages：32 Language：English Book type：Scholarly book
Nanobiomaterials: Nanostructured Materials for Biomedical Applications
Shohei Ishikawa, Kazutoshi Iijima, Hidenori Otsuka（ Role： Joint author , Chapter 17 "Nanofabrication Technologies for Controlled Cell Tissue Engineering and Bioapplication）
Elsevier Ltd. （ ISBN:9780081007167 ）
Responsible for pages：385-409 Language：English Book type：Scholarly book
Iijima, M; Sato, M; Wakabayashi, H; Kojima, K; Togashi, K; Oishi, S; Misu, T; Mukai, M; Miyajima, H … Show more authors
Iijima, M; Sato, M; Wakabayashi, H; Kojima, K; Togashi, K; Oishi, S; Misu, T; Mukai, M; Miyajima, H; Maruo, S; Iijima, K Hide authors
ACS BIOMATERIALS SCIENCE & ENGINEERING 2025.4 [Reviewed]
Authorship：Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Joint Work
Sugimoto-Sawada, Y; Yamashiro, M; Kono, M; Ikeda, H; Itagaki, H; Iijima, K
TOXICOLOGY IN VITRO 106 2025.6 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
Effect of anionic polyelectrolytes on formation of hydroxyapatite particles in simulated body fluids
Sagawa, T; Kako, N; Nakaya, M; Izumi, T; Takeda, K; Iijima, K; Hashizume, M
JOURNAL OF ASIAN CERAMIC SOCIETIES 13 ( 1 ) 1 - 9 2025.1 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells
Nishida, A; Sawada, Y; Arai, R; Ishibashi, N; Suzuo, M; Ohno, A; Ashikaga, T; Iijima, K
FRONTIERS IN TOXICOLOGY 6 2024.7 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
Fabrication of Hydroxyapatite-Modified Fluorescent Nanorods and Their Application to Drug Carriers
SAGAWA Takuya, YAMAGUCHI Hutoshi, SUZUKI Tomohiko, IIJIMA Kazutoshi, YATAKA Yusuke, HASHIZUME Mineo
Journal of the Japan Society of Colour Material 97 ( 2 ) 39 - 45 2024.2 [Reviewed]
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Society of Colour Material Joint Work
<p>Inorganic fluorescent materials are excellent in monochromaticity and durability. Therefore, they are expected to be used as bioprobes. In this study, biocompatible and pH-responsive fluorescent inorganic nanorods were fabricated by modification of the surface of europium hydroxide nanorods (ENRs) with hydroxyapatite (HAp). One method to deposit HAp on ENR surfaces was that using immersion in simulated body fluids (SBFs) and the other was that using alternate soaking process (ASP). In the method using SBFs, HAp deposition was observed but they did not fully cover the surface of ENR. On the other hand, the surface of ENR was covered with HAp entirely, and the coating amount depended on the number of cycles of ASP. Furthermore, the adsorption of proteins such as fluorescein-loaded bovine serum albumin and cytochrome C on HAp-modified ENR was confirmed. The release behavior of these protein changed depending on the isoelectric point of the protein and the pH of the solution. The present results indicate potential application of these HAp-modified ENRs as a fluorescent, pH-responsive drug carrier.</p>
Cell Scaffolds for Bone Tissue Engineering
Iijima Kazutoshi, Otsuka Hidenori
BIOENGINEERING-BASEL 7 ( 4 ) 2020.12
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution) Joint Work
ペプチド・タンパク質を利用した高分子材料表面へのヒドロキシアパタイト複合化とその生物医学的応用, C&I Commun., 43(3), 19–21 (2018).
飯島一智
Colloid and Interface Communication 43 ( 3 ) 19 - 21 2018.8
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Publisher：日本化学会コロイドおよび界面化学部会 Single Work
Fibrous Materials in Regenerative Medicine
Kazutoshi Iijima, Shohei Ishikawa, Hidenori Otsuka
J. Jpn. Soc. Colour. Mater. 91 ( 8 ) 274 - 277 2018.8 [Reviewed] [Invited]
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Publisher：Japan Society of Colour Material Joint Work
Fiber materials have been used not only for clothing applications but also in many other industrial fields such as "aviation and space", "mechanical industry", "electronics and communication" and "medicine". In recent years, fiber materials have attracted much attention as cell scaffold materials in medicine, particularly in regenerative medicine. In this paper, the current status of application of fiber materials such as nonwoven fabrics and hydrogels of nanofibers of biopolymers and biodegradable synthetic polymers in regenerative medicine is explained. Recent advances by the authors in three dimensional culture of cells using silica nano nonwoven fabric will be also addressed.Fiber materials have been used not only for clothing applications but also in many other industrial fields such as "aviation and space", "mechanical industry", "electronics and communication" and "medicine". In recent years, fiber materials have attracted much attention as cell scaffold materials in medicine, particularly in regenerative medicine. In this paper, the current status of application of fiber materials such as nonwoven fabrics and hydrogels of nanofibers of biopolymers and biodegradable synthetic polymers in regenerative medicine is explained. Recent advances by the authors in three dimensional culture of cells using silica nano nonwoven fabric will be also addressed.
Creation of peptide-hydroxyapatite nanohybrids by biomimetic processes
Kazutoshi Iijima, Mineo Hashizume
3 ( 1 ) 8 - 16 2018.1 [Reviewed] [Invited]
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Joint Work
Utilization of Proteins and Peptides to Create Organic-Hydroxyapatite Hybrids.
Kazutoshi Iiiima, Hashizume Mineo
Protein & Peptide Letters 25 25 - 33 2018 [Reviewed] [Invited]
Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Joint Work
ポリイオンコンプレックス、及びポリイオンコンプレックスの成形体
橋詰峰雄, 飯島一智, 榊原みなみ, 吉田英人, 阿部友紀奈
Application no：特願2017-230499 Date applied：2017.11.30
Announcement no：特開2019-099652 Date announced：2019.6.24
Country of applicant：Domestic
日化協 LRI賞
2023.11 日本動物実験代替法学会 Fabricating a novel three dimensional skin model using silica nonwoven fabrics (SNF)
Individual or group name of awards：飯島一智
SPSJ Award for the Outstanding Paper in Polymer Journal sponsored by ZEON
2019.5 The Society of Polymer Science, Japan (SPSJ)
Individual or group name of awards：Kazutoshi Iijima
膝関節再生を志向した間葉系幹細胞の分化制御と移植用組織の構築
2019.4 - 2022.3
科学研究費補助金 Grant-in-Aid for Scientific Research(C)
Investigator(s)：飯島一智
Grant type：Competitive
新規ハイブリッド足場材料を用いた間葉系幹細胞の分化制御
2015.4 - 2018.3
科学研究費補助金 Grant-in-Aid for Scientific Research(C)
Investigator(s)：飯島一智
Grant type：Competitive
小児急性リンパ性白血病新規キメラ分子SNX2-ABL1の機能の解明
2013.4 - 2015.3
科学研究費補助金 Grant-in-Aid for Young Scientists(B)
Investigator(s)：飯島一智
Grant type：Competitive
Bリンパ腫特異的新規ジンクフィンガー蛋白のB細胞分化、腫瘍特性における意義の解明
2011.4 - 2013.3
科学研究費補助金 Grant-in-Aid for Young Scientists(B)
Investigator(s)：飯島一智
Grant type：Competitive
配向組織構築を志向した流路を用いた三次元配向コラーゲンハイドロゲルの作製における流路径や流速の影響の詳細な検討
飯島瑞稀, 若林保志, 小島加帆里, 大石翔心, 三須匠, 宮島浩樹, 向井理, 丸尾昭二, 飯島一智
化学工学会第90年会
Event date： 2025.3
Language：Japanese Presentation type：Poster presentation
Design, Photo-fabrication and Characterization of Photo-decomposable Gelatin-based Hydrogel Cell Scaffolds
Hiroki Miyajima, Chisato Handa, Noemi Bata Hikuma, Shogo Oishi, Yuki Hatta,Kaori Kojima, Masaru Mukai, Shoji Maruo, Kazutoshi Iijima [Invited]
International Symposium on Exponential Biomedical DX 2024 (eMEDX-24)
Event date： 2024.12
Language：English Presentation type：Oral presentation (invited, special)
組織工学応用に向けたゼラチンメタクリレート/多糖複合ハイドロゲルの光造形
飯沼千佳, 小野寺晃大, 富田晃生, 小島加帆里, 宮島浩樹, 向井理, 丸尾昭二, 飯島一智
第34回日本MRS年次大会
Event date： 2024.12
Language：English Presentation type：Oral presentation (general)
キトサンと種々のアニオン性多糖からなる高分子電解質錯体微粒子の水溶媒中における粒子径および分散状態の解析と水和状態の考察
北由弥香, 飯島一智
第62回水と高分子に関する討論会
Event date： 2024.12
Language：Japanese Presentation type：Poster presentation
ナノマテリアル吸入毒性試験法の開発に向けた、各種シリカナノ粒子曝露によるTHP-1 細胞活性化のメカニズム解析と新規評価指標候補遺伝子の発現解析
荒井りおん, 大野 彰子, 足利太可雄, 飯島一智
日本動物実験代替法学会 第37回大会
Event date： 2024.11 - 2024.12
Language：Japanese Presentation type：Poster presentation
2025 Medical Engineering
College of Engineering Science
2025 Chemistry, Chemical Engineering and Life Science: Exercise A
College of Engineering Science
2025 Bioscience Research Ⅹ
College of Engineering Science
2025 Bioscience Research Ⅸ
College of Engineering Science
2025 Bioscience Research Ⅷ
College of Engineering Science
動物実験代替法学会
2019.1 - 2020.12 企画委員会委員
Committee type：Academic society
微細なハイドロゲル ３次元モデルを無機複合化 横浜国大が技術開発
科学新聞、Science Japan（JST） 2024.3
ハイドロゲル被覆 ３Dプリンター活用 骨髄の代替材へ応用 横浜国大
日刊工業新聞 2024.2
Author：Other
