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IIJIMA Kazutoshi
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【Published Thesis】 Hydroxyapatite Particles from Simulated Body Fluids with Different pH and Their Effects on Mesenchymal Stem Cells 2021.09
【Published Thesis】 Fabrication and Characterization of Polysaccharide Composite Films from Polyion Complex Particles 2020.02
【Published Thesis】 Analysis of the formation mechanism of polyion complexes of polysaccharides by molecular dynamics simulation with oligosaccharides 2022.03
【Published Thesis】 Analysis of the formation mechanism of polyion complexes of polysaccharides by molecular dynamics simulation with oligosaccharides 2022.03
【Published Thesis】 Hydroxyapatite Particles from Simulated Body Fluids with Different pH and Their Effects on Mesenchymal Stem Cells 2021.09
【Published Thesis】 Fabrication and Characterization of Polysaccharide Composite Films from Polyion Complex Particles 2020.02
【Published Thesis】 Specific ion effects on the aggregation of polysaccharide-based polyelectrolyte complex particles induced by monovalent ions within Hofmeister series(JOURNAL OF COLLOID AND INTERFACE SCIENCE) 2023.08
【Published Thesis】 Analysis of the aggregation mechanism of chondroitin sulfate/chitosan particles and fabrication of hydrogel cell scaffolds(INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES) 2022.06
Doctor of Engineering - Keio University
Master of Engineering - Keio University
Duty Yokohama National UniversityFaculty of Engineering Division of Materials Science and Chemical Engineering Associate Professor
Concurrently Yokohama National UniversityInstitute of Advanced Sciences Associate Professor
Concurrently Yokohama National UniversityGraduate School of Engineering Department of Materials Science and Engineering Associate Professor
Concurrently Yokohama National UniversityCollege of Engineering Science Department of Chemistry, Chemical Engineering and Life Science Associate Professor
Concurrently Yokohama National UniversityGraduate school of Engineering Science Department of Chemistry, Chemical Engineering and Life Science Associate Professor
Nanostructured Materials: Synthesis, Properties and Applications
Mineo Hashizume,Kazutoshi Iijima,Yusuke Yataka（ Role： Contributor）
NOVA science publishers （ ISBN:978-1-53615-013-1 ）
Language：English Book type：Scholarly book
ドラッグデリバリーシステム-バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発-
（ Role： Contributor）
シーエムシー出版 （ ISBN:9784781313337 ）
Language：Japanese Book type：Scholarly book
Advances in Chemistry Research
Shohei Ishikawa, Kazutoshi Iijima, Yuta Yahagi, Hidenori Otsuka（ Role： Joint author）
Nova Science Publishers （ ISBN:9781536138382 ）
Total pages：264 Responsible for pages：32 Language：English Book type：Scholarly book
Nanobiomaterials: Nanostructured Materials for Biomedical Applications
Shohei Ishikawa, Kazutoshi Iijima, Hidenori Otsuka（ Role： Joint author , Chapter 17 "Nanofabrication Technologies for Controlled Cell Tissue Engineering and Bioapplication）
Elsevier Ltd. （ ISBN:9780081007167 ）
Responsible for pages：385-409 Language：English Book type：Scholarly book
Stimuli-Responsive Interfaces: Fabrication and Application
Mineo Hashizume, Iijima Kazutoshi（ Role： Sole author , Chapter 15 "Media-Responsive Swelling and Material Release Properties of Polysaccharide Composite Films）
Springer Nature Singapore （ ISBN:978-981-10-24 ）
Responsible for pages：269-279 Language：English Book type：Scholarly book
Fabrication of Hydroxyapatite-Modified Fluorescent Nanorods and Their Application to Drug Carriers
SAGAWA Takuya, YAMAGUCHI Hutoshi, SUZUKI Tomohiko, IIJIMA Kazutoshi, YATAKA Yusuke, HASHIZUME Mineo
Journal of the Japan Society of Colour Material 97 ( 2 ) 39 - 45 2024.2 [Reviewed]
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Society of Colour Material Joint Work
<p>Inorganic fluorescent materials are excellent in monochromaticity and durability. Therefore, they are expected to be used as bioprobes. In this study, biocompatible and pH-responsive fluorescent inorganic nanorods were fabricated by modification of the surface of europium hydroxide nanorods (ENRs) with hydroxyapatite (HAp). One method to deposit HAp on ENR surfaces was that using immersion in simulated body fluids (SBFs) and the other was that using alternate soaking process (ASP). In the method using SBFs, HAp deposition was observed but they did not fully cover the surface of ENR. On the other hand, the surface of ENR was covered with HAp entirely, and the coating amount depended on the number of cycles of ASP. Furthermore, the adsorption of proteins such as fluorescein-loaded bovine serum albumin and cytochrome C on HAp-modified ENR was confirmed. The release behavior of these protein changed depending on the isoelectric point of the protein and the pH of the solution. The present results indicate potential application of these HAp-modified ENRs as a fluorescent, pH-responsive drug carrier.</p>
Miyajima, H; Kojima, K; Touji, H; Onodera, K; Mukai, M; Maruo, S; Iijima, K
ACS BIOMATERIALS SCIENCE & ENGINEERING 10 ( 2 ) 762 - 772 2023.11 [Reviewed]
Authorship：Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Joint Work
Specific ion effects on the aggregation of polysaccharide-based polyelectrolyte complex particles induced by monovalent ions within Hofmeister series
Yamazaki Makoto, Yabe Makoto, Iijima Kazutoshi
JOURNAL OF COLLOID AND INTERFACE SCIENCE 643 305 - 317 2023.8 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
Fabrication of Polysaccharide-Based Coaxial Fibers Using Wet Spinning Processes and Their Protein Loading Properties
Sagawa Takuya, Morizumi Hiroki, Iijima Kazutoshi, Yataka Yusuke, Hashizume Mineo
APPLIED SCIENCES-BASEL 13 ( 14 ) 2023.7 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
Three-dimensional co-culture model employing silica nonwoven fabrics to enhance cell-to-cell communication of paracrine signaling between hepatocytes and fibroblasts
Ishikawa Shohei, Iijima Kazutoshi, Sasaki Kohei, Kawabe Masaaki, Osawa Shigehito, Otsuka Hidenori
BIOTECHNOLOGY AND BIOENGINEERING 120 ( 7 ) 1961 - 1974 2023.7 [Reviewed]
Language：English Publishing type：Research paper (scientific journal) Joint Work
Cell Scaffolds for Bone Tissue Engineering
Iijima Kazutoshi, Otsuka Hidenori
BIOENGINEERING-BASEL 7 ( 4 ) 2020.12
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution) Joint Work
ペプチド・タンパク質を利用した高分子材料表面へのヒドロキシアパタイト複合化とその生物医学的応用, C&I Commun., 43(3), 19–21 (2018).
飯島一智
Colloid and Interface Communication 43 ( 3 ) 19 - 21 2018.8
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Publisher：日本化学会コロイドおよび界面化学部会 Single Work
Fibrous Materials in Regenerative Medicine
Kazutoshi Iijima, Shohei Ishikawa, Hidenori Otsuka
J. Jpn. Soc. Colour. Mater. 91 ( 8 ) 274 - 277 2018.8 [Reviewed] [Invited]
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Publisher：Japan Society of Colour Material Joint Work
Fiber materials have been used not only for clothing applications but also in many other industrial fields such as "aviation and space", "mechanical industry", "electronics and communication" and "medicine". In recent years, fiber materials have attracted much attention as cell scaffold materials in medicine, particularly in regenerative medicine. In this paper, the current status of application of fiber materials such as nonwoven fabrics and hydrogels of nanofibers of biopolymers and biodegradable synthetic polymers in regenerative medicine is explained. Recent advances by the authors in three dimensional culture of cells using silica nano nonwoven fabric will be also addressed.Fiber materials have been used not only for clothing applications but also in many other industrial fields such as "aviation and space", "mechanical industry", "electronics and communication" and "medicine". In recent years, fiber materials have attracted much attention as cell scaffold materials in medicine, particularly in regenerative medicine. In this paper, the current status of application of fiber materials such as nonwoven fabrics and hydrogels of nanofibers of biopolymers and biodegradable synthetic polymers in regenerative medicine is explained. Recent advances by the authors in three dimensional culture of cells using silica nano nonwoven fabric will be also addressed.
Creation of peptide-hydroxyapatite nanohybrids by biomimetic processes
Kazutoshi Iijima, Mineo Hashizume
3 ( 1 ) 8 - 16 2018.1 [Reviewed] [Invited]
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Joint Work
Fibrous Materials in Regenerative Medicine
Kazutoshi Iijima, Shohei Ishikawa, Hidenori Otsuka
Journal of the Japan Society of Colour Material 91 ( 8 ) 1 - 4 2018 [Reviewed] [Invited]
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Publisher：Japan Society of Colour Material Joint Work
ポリイオンコンプレックス、及びポリイオンコンプレックスの成形体
橋詰峰雄, 飯島一智, 榊原みなみ, 吉田英人, 阿部友紀奈
Application no：特願2017-230499 Date applied：2017.11.30
Announcement no：特開2019-099652 Date announced：2019.6.24
Country of applicant：Domestic
SPSJ Award for the Outstanding Paper in Polymer Journal sponsored by ZEON
2019.5 The Society of Polymer Science, Japan (SPSJ)
Individual or group name of awards：Kazutoshi Iijima
膝関節再生を志向した間葉系幹細胞の分化制御と移植用組織の構築
2019.4 - 2022.3
科学研究費補助金 Grant-in-Aid for Scientific Research(C)
Investigator(s)：飯島一智
Grant type：Competitive
新規ハイブリッド足場材料を用いた間葉系幹細胞の分化制御
2015.4 - 2018.3
科学研究費補助金 Grant-in-Aid for Scientific Research(C)
Investigator(s)：飯島一智
Grant type：Competitive
小児急性リンパ性白血病新規キメラ分子SNX2-ABL1の機能の解明
2013.4 - 2015.3
科学研究費補助金 Grant-in-Aid for Young Scientists(B)
Investigator(s)：飯島一智
Grant type：Competitive
Bリンパ腫特異的新規ジンクフィンガー蛋白のB細胞分化、腫瘍特性における意義の解明
2011.4 - 2013.3
科学研究費補助金 Grant-in-Aid for Young Scientists(B)
Investigator(s)：飯島一智
Grant type：Competitive
マイクロ光造形ハイドロゲルで形作る骨微細モデル
宮島浩樹, 田路弘樹, 小島加帆理, 向井理, 丸尾昭二, 飯島一智
日本化学会 第103春季年会
Event date： 2023.3
Language：Japanese Presentation type：Poster presentation
Venue：千葉県野田市 東京理科大学野田キャンパス
Simple Fabrication Strategy for Biomaterials Utilizing Polyelectrolyte Complex of Polysaccharide
Kazutoshi Iijima, Makoto Yamazaki [Invited]
YNU International Symposium 2022
Event date： 2022.12
Language：English Presentation type：Oral presentation (invited, special)
Venue：横浜市保土ケ谷区 横浜国立大学常盤台キャンパス
Relationship between androgen dependence and sebaceous secretion sensitivity in prostate cancer
Haruka Takahashi, Mizuki Nakahama, Unhwa Lee, Masatoshi Watanabe, Kazutoshi Iijima
YNU International Symposium 2022
Event date： 2022.12
Language：English Presentation type：Poster presentation
Venue：横浜市保土ケ谷区 横浜国立大学常盤台キャンパス
Regeneration of bone-cartilage continuum tissue using chitosan-hyaluronic acid hydrogel
Kodai Onodera, Kazuki Yamauchi, Kazutoshi Iijima
YNU International Symposium 2022
Event date： 2022.12
Language：English Presentation type：Poster presentation
Venue：横浜市保土ケ谷区 横浜国立大学常盤台キャンパス
Photo-responsive Hydrogels of Gelatin with Photocleavable moiety
Hiroki Miyajima, Saeka Kato, Akihito Shibui, Chisato Handa, Kazutoshi Iijima (presenter) [Invited]
BIO-Remedi 2022
Event date： 2022.12
Language：English Presentation type：Oral presentation (keynote)
Venue：IIT guwahati, Guwahati, India Country：India
2024 Bioscience Research Ⅰ
College of Engineering Science
2024 Research Methodology for Biological Sciences
College of Engineering Science
2024 Basic Laboratory of Bio Educational Program
College of Engineering Science
2024 Bioscience Research Ⅱ
College of Engineering Science
2024 Engineering in Biology, Medicine and Bioanalytical Chemistry, Practice F
Graduate school of Engineering Science
動物実験代替法学会
2019.1 - 2020.12 企画委員会委員
Committee type：Academic society
